DBCO-Lys(m-PEG4)-Val-Ala-PAB dbco-dap-m-PEG4 Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Synonyms CAS

Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C81H135N13O22 Molecular Weight 1643

512 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

93 SMILES ClCCOCCOCCOCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

568 Purity (HPLC) >= 95% Solubility DMSO

DBCO-Lys(m-PEG4)-Val-Ala-PAB dbco-dap-m-PEG4 Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,