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Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4) cr6g Product Name Pomalidomide-C4-Br Synonyms Pomalidomide-4'-C4-Br

SKU 94557532260
4.3
USD195.00 USD219.00

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Description

Product Name Pomalidomide-C4-Br Synonyms Pomalidomide-4'-C4-Br CAS Number 2355289-79-9 Related CAS Molecular Formula C17H18BrN3O4 Molecular Weight 408

Product Name DOTA-PEG6 Synonyms CAS Number n/a Related CAS Molecular Formula C28H53N5O13 Molecular Weight 667

Product Name Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C48H71N7O18 Molecular Weight 1034

789 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4) cr6g Product Name Pomalidomide-C4-Br Synonyms Pomalidomide-4'-C4-BrSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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