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Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Lenalidomide-CO-C4-alkyne Synonyms Lenalidomide-4'-CO-C4-alkyne

SKU 93847237219
4.1
EUR445.00 EUR477.00

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Ships within 48 hours · Estimated delivery Aug 18 - Aug 23

Description

Product Name Lenalidomide-CO-C4-alkyne Synonyms Lenalidomide-4'-CO-C4-alkyne CAS Number n/a Related CAS Molecular Formula C20H21N3O4 Molecular Weight 367

Product Name tert-butyl N-{2-[2-(piperazin-1-yl)ethoxy]ethyl}carbamate Synonyms CAS Number n/a Related CAS Molecular Formula C13H27N3O3 Molecular Weight 273

85 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCCN=[N]#N)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

295 SMILES OC(=O)CCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Lenalidomide-CO-C4-alkyne Synonyms Lenalidomide-4'-CO-C4-alkyneSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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