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1126/sciadv
Product Name Thalidomide-O-PEG2-C2-acid Synonyms Thalidomide-4'-O-PEG2-C2-acid CAS Number 2488752-64-1 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434
336 SMILES CC(C)(C)OC(=O)CCCN1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C78H107FN10O26 Molecular Weight 1619
DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg 1126/sciadvSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
