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A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase
31 SMILES FC(F)(F)C1=CC(SC2=C(Cl)C=CC=C2Cl)=C(C(=O)N2CC3=CC=CC(C#N)=C3C2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
S)-AHPC-CO-PEG4-C2-amine HCl Synonyms CAS Number 2349429-70-3 Related CAS Molecular Formula C33H52ClN5O8S Molecular Weight 714
GW5074 reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)
Thalidomide-5'-piperazine-C2-piperazine HCl e3 A novel cereblon modulator recruitsProtein degrader building block. Contains cereblon ligand Thalidomid and 5' substituted heterocyclic linker. Product Name Thalidomide 5' piperazine C2 piperazine HCl Synonyms CAS Number n a Related CAS Molecular Formula C23H33Cl3N6O4 Molecular Weight 563. 91 SMILES Cl. Cl. Cl. O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(=CC=C12)N1CCN(CCN2CCNCC2)CC1 Purity (HPLC) 95% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For
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