DOTA-C6-propanamido-maleimide crbn NRX-103095 acts as molecular glue

NRX-103095 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

planar structure around the boron-dipyrromethene core imparts exceptional photostability

NCCOCCOCCOCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

8 SMILES Cl

DOTA-C6-propanamido-maleimide crbn NRX-103095 acts as molecular glueDOTA bifucational chelator containing a thiol reactive maleimide group, an alkyl linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA C6 propanamido maleimide (TFA salt) Synonyms CAS Number n a Related CAS Molecular Formula