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Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE featured S)-AHPC-CO-C6-Br Synonyms CAS Number n/a

SKU 8619429204
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Description

S)-AHPC-CO-C6-Br Synonyms CAS Number n/a Related CAS Molecular Formula C29H41BrN4O4S Molecular Weight 621

Product Name DOTA-heptyne Synonyms CAS Number n/a Related CAS Molecular Formula C23H39N5O7 Molecular Weight 497

S)-AHPC-CO-PEG1-propargyl Synonyms CAS Number 2242965-71-3 Related CAS Molecular Formula C28H36N4O5S Molecular Weight 540

Product Name MC-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C45H62N8O16 Molecular Weight 971

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE featured S)-AHPC-CO-C6-Br Synonyms CAS Number n/aSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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