DOTA-tris(t-Bu)ester-butyne Size:25mg NRX-2663 acts as molecular glue

NRX-2663 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Locally Advanced or Metastatic Breast Cancer

Product Name DOTA-tris(t-Bu)ester-heptyne Synonyms CAS Number n/a Related CAS Molecular Formula C35H63N5O7 Molecular Weight 665

DOTA-tris(t-Bu)ester-butyne Size:25mg NRX-2663 acts as molecular glueDOTA bifucational chelator containing an alkyne group, an alkyl linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA tris(t Bu)ester butyne Synonyms CAS Number 2125661 54 1 Related CAS Molecular Formula C32H57N5O7 Molecular