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Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE ca Product Name: 5(6)-FAM PEG3 alkyne

SKU 82281863698
4.2
USD495.00 USD517.00

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Description

Product Name: 5(6)-FAM PEG3 alkyne Synonyms: 5-(and 6)-Carboxyfluorescein-PEG3-alkyne CAS Number: N/A Molecular Formula: C30H27NO9 Molecular Weight: 545

DOTA bifucational chelator containing an amine-reactive NHS group

Product Name 5-(Methoxy-d3)-2-methylaniline Synonyms CAS Number n/a Related CAS Molecular Formula C8H11NO Molecular Weight 140

and drug development

Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE ca Product Name: 5(6)-FAM PEG3 alkyneSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl

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