Phthalimidinoglutarimide-5'-propargyl-C2-OH fluorescent SHP099 suppresses RAS–ERK signalling to

SHP099 suppresses RAS–ERK signalling to inhibit the proliferation of receptor-tyrosine-kinase-driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models

56 SMILES Cl

S)-AHPC-CO-C4-acid Synonyms CAS Number 2172819-74-6 Related CAS Molecular Formula C28H38N4O6S Molecular Weight 558

168 SMILES [2H]C([2H])([2H])OC1=CC=C(C=C1)C#N Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Phthalimidinoglutarimide-5'-propargyl-C2-OH fluorescent SHP099 suppresses RAS–ERK signalling toDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Phthalimidinoglutarimide 5' propargyl C2 OH Synonyms CAS Number 2229714 98 9 Related CAS Molecular Formula C18H18N2O4 Molecular Weight 326. 352 SMILES OCCCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping