Azide-Dap(m-PEG4)-Val-Ala-PAB-PNP alkene 1038/s41586-019-1722-1

1038/s41586-019-1722-1

7554/eLife

Product Name Pomalidomide-5'-C3-amine HCl Synonyms CAS Number n/a Related CAS 2412056-37-0 (free base) Molecular Formula C16H19ClN4O4 Molecular Weight 366

Product Name Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C79H125N11O22 Molecular Weight 1580

Azide-Dap(m-PEG4)-Val-Ala-PAB-PNP alkene 1038/s41586-019-1722-1SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine