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TAMRA TMR) is a bright orange fluorophore and one of the most popular fluorophores used in various bioconjugations
The payload is monomethyl auristatin E (MMAE)
It is also a good transglutaminase substrate
The PNP (para-nitrophenyl) moiety serves as an activating leaving group
Val-Cit-PAB mal-lys-m-peg4 TAMRA TMR) is a brightVal Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug. Product Name Val Cit PAB Synonyms VC PAB OH CAS Number 159857 79 1 Related CAS Molecular Formula C18H29N5O4 Molecular Weight 379. 461 Purity (HPLC) >= 95% Solubility DMSO, DMF Shipping
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