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Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine Product Name DOTA-PEG2-C2-propanamido-maleimide Synonyms CAS

SKU 72843421524
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Description

Product Name DOTA-PEG2-C2-propanamido-maleimide Synonyms CAS Number Related CAS Molecular Formula C29H47N7O12 Molecular Weight 685

442 Purity (HPLC) >= 95% Solubility DMSO

177 SMILES [2H]C([2H])([2H])N1CCN(CC1)C1=CC=C(Br)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Sci Transl Med 2021

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine Product Name DOTA-PEG2-C2-propanamido-maleimide Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous

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