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Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C94H155N13O29 Molecular Weight 1931
Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay
O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(=CC=C12)N1CCNCC1 Purity (HPLC) 95% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only
Product Name Lenalidomide-CO-PEG1-C2-Cl Synonyms Lenalidomide-4'-CO-PEG1-C2-Cl CAS Number n/a Related CAS Molecular Formula C18H20ClN3O5 Molecular Weight 393
Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan protac Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by
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