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Product Name Lenalidomide-5'-CO-C3-alkyne Synonyms CAS Number n/a Related CAS Molecular Formula C19H19N3O4 Molecular Weight 353
Product Name Pomalidomide-5'-PEG5-OH Synonyms CAS Number 2641838-56-2 Related CAS Molecular Formula C23H31N3O9 Molecular Weight 493
It binds to the VHL E3 ligase with an IC50 of 0
Product Name Thalidomide-5'-O-PEG2-OH Synonyms CAS Number 2328212-84-4 Related CAS Molecular Formula C17H18N2O7 Molecular Weight 362
Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Lenalidomide-5'-CO-C3-alkyne Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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