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where PC-6 is converted into a positively charged product (PAD6) upon incorporation into NAD
Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C92H141N13O26 Molecular Weight 1845
making the linkers highly adaptable for diverse ADC and related applications
and cell death
Azide-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8) probe where PC-6 is converted intoSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through
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