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Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Size:100mg 3-triazole linkages

SKU 6504175517
4.8
USD245.00 USD285.00

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Description

3-triazole linkages

3-dione Synonyms 1-(²H3)methyl-2

394 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C1C=CC=C2NCC1=CC2=CC=CC=C2O1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Product Name Thalidomide-propargyl-O-PEG2-C2-amine HCl Synonyms Thalidomide-4'-propargyl-O-PEG2-C2-amine HCl CAS Number n/a Related CAS Molecular Formula C22H26ClN3O7 Molecular Weight 479

Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Size:100mg 3-triazole linkagesSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility.

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