Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP protac precursor Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB-PNP Synonyms CAS

Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C38H54N10O14 Molecular Weight 874

Contains an E3 ligase ligand with PEG linker and terminal alcohol

308 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(OCCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-PEG1-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C21H35N5O8 Molecular Weight 485

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP protac precursor Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB-PNP Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine