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Product Name DOTA-PEG2-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C22H40N8O9 Molecular Weight 560
Building Block for DACF1 Binders and PROTACs based on DACF1 Binders
Product Name Thalidomide-5'-O-PEG6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C25H34N2O11 Molecular Weight 538
Distinct beta-arrestin coupling and intracellular trafficking of metabotropic glutamate receptor homo-and heterodimers
DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:25mg Product Name DOTA-PEG2-C2-azide Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU
