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DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP linker NCCOCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC): 95% Shipping

SKU 5889665728
4.0
EUR445.00 EUR491.00

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Description

NCCOCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC): 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

The payload is monomethyl auristatin E (MMAE)

Product Name Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C90H147N13O27 Molecular Weight 1843

CDg18 is the first M2 macrophage selective fluorescent probe

DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP linker NCCOCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC): 95% ShippingSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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