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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Size:25mg 294 Purity (HPLC) >= 95%

SKU 49793155577
4.8
EUR495.00 EUR522.00

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Ships within 48 hours · Estimated delivery Aug 20 - Aug 25

Description

294 Purity (HPLC) >= 95% Solubility DMSO

which binds to DCAF1 with a Kd by SPR and IC50 by TR-FRET of <50 nM

Product Name MaP555-Alkyne Synonyms CAS Number n/a Related CAS Molecular Formula C30H31N5O5S Molecular Weight 573

BODIPY (boron-dipyrromethene

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Size:25mg 294 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by

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