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Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4)-MMAE Size:10mg Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS

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Description

Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C94H155N13O29 Molecular Weight 1931

Product Name Phthalimidinoglutarimide-propargyl-PEG2-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG2-OH CAS Number n/a Related CAS Molecular Formula C20H22N2O6 Molecular Weight 386

SiR650 Acid CAS Number 1426090-03-0 Related CAS N/A Molecular Formula C27H28N2O4Si Molecular Weight 472

458 SMILES CC(C)(C)OC(=O)CN1CCN(CCN2CCNCC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4)-MMAE Size:10mg Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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