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Product Name Thalidomide-O-acetamido-PEG5-C2-acid Synonyms Thalidomide-4'-O-acetamido-PEG5-C2-acid CAS Number n/a Related CAS Molecular Formula C28H37N3O13 Molecular Weight 623
9 SMILES ClCCOCCOCCOCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
It can be used in many different diagnostic and therapeutic applications
Sci Transl Med 2021
Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE exatecan Product Name Thalidomide-O-acetamido-PEG5-C2-acid Synonyms Thalidomide-4'-O-acetamido-PEG5-C2-acidSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is
