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Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg BC-Nor is a CLIP-tag substrate

SKU 42073577170
4.1
USD445.00 USD494.00

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Description

BC-Nor is a CLIP-tag substrate containing norbornene moiety for click chemistry applications

Product Name Thalidomide-O-acetamido-PEG3-OH Synonyms Thalidomide-4'-O-acetamido-PEG3-OH CAS Number n/a Related CAS Molecular Formula C21H25N3O9 Molecular Weight 463

S)-AHPC-CO-PEG3-propargyl Synonyms CAS Number 2374122-30-0 Related CAS Molecular Formula C32H44N4O7S Molecular Weight 628

propargylamide CAS Number: 510758-19-7 Molecular Formula: C24H15NO6 Molecular Weight: 413

Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg BC-Nor is a CLIP-tag substrateSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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