TMP3-TMR Size:100nmol S)-AHPC-CO-C5-NH2 HCl Synonyms CAS Number

S)-AHPC-CO-C5-NH2 HCl Synonyms CAS Number 2415256-20-9 Related CAS 2170695-19-7 (free base) Molecular Formula C28H43Cl2N5O4S Molecular Weight 616

Targeted protein degraders crowd into the clinic

116 SMILES [2H]C([2H])([2H])N(C1=CC=CC(Br)=C1)C([2H])([2H])[2H] Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

38 SMILES: Cl

TMP3-TMR Size:100nmol S)-AHPC-CO-C5-NH2 HCl Synonyms CAS NumberThe TMP tag is based on the tight binding between trimethoprim (TMP), a synthetic antibiotic, and Escherichia coli dihydrofolate reductase (eDHFR), a small enzyme with a high affinity for TMP. By fusing eDHFR to a protein of interest and introducing TMP linked to a probesuch as a fluorescent dye, biotin, or other functional groupresearchers can selectively label and study proteins in their native cellular environment. TMP3 TMR is a third generation