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Product Name DOTA-C5-alcohol Synonyms CAS Number n/a Related CAS Molecular Formula C21H39N5O8 Molecular Weight 489
294 Purity (HPLC) >= 95% Solubility DMSO
Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody–drug conjugate (ADC) development
388 Purity (HPLC) >= 95% Solubility DMSO
Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:10mg Product Name DOTA-C5-alcohol Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a
