MC-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg BG-TCO is a SNAP-tag substrate

BG-TCO is a SNAP-tag substrate containg TCO moiety for click chemistry chemistry applications

Product Name Phthalimidinoglutarimide-propargyl-PEG1-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG1-OH CAS Number n/a Related CAS Molecular Formula C18H18N2O5 Molecular Weight 342

453 SMILES OC(=O)CCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NCCCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

MC-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg BG-TCO is a SNAP-tag substrateSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate