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Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-MMAE Size:25mg BG-Oregon Green is a SNAP-tag

SKU 39010314651
4.2
USD445.00 USD479.00

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Description

BG-Oregon Green is a SNAP-tag substrate containg Oregon Green Dye

The conventional maleimidocaproyl (MC) unit is replaced by Mal-Propionyl-PEG2 moiety to enhance aqueous solubility

968 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

48 SMILES Cl

Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-MMAE Size:25mg BG-Oregon Green is a SNAP-tagSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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