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DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg 68 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC)

SKU 33203510676
4.8
USD445.00 USD489.00

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Description

68 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Cy3-CA CAS Number Related CAS Molecular Formula C40H57ClN3O3 Molecular Weight 663

Product Name Phthalimidinoglutarimide-propargyl-C2-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-C2-OH CAS Number 2138441-30-0 Related CAS Molecular Formula C18H18N2O4 Molecular Weight 326

Sulforhodamine 101 azide (Texes Red azide) is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry

DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg 68 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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