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SPAAC is copper-free
Beyond monitoring protein aggregation
making it a powerful tool for monitoring SARM1 activation in biochemical assays
Product Name Thalidomide-5'-piperidine-acid Synonyms CAS Number 2467965-70-2 Related CAS Molecular Formula C19H19N3O6 Molecular Weight 385
DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) chelator SPAAC is copper-freeSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
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