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HB007 induces ubiquitination and degradation of SUMO1
Journal of Hematology & Oncology 2021
Product Name Lenalidomide-acetamido-O-C2-Cl Synonyms Lenalidomide-4'-acetamido-O-C2-Cl CAS Number n/a Related CAS Molecular Formula C17H18ClN3O5 Molecular Weight 379
Tunnermann
DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP Size:100mg HB007 induces ubiquitination and degradationSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
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