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Cy3 CAS Number: N/A Molecular Formula: C32H40N2O5S Molecular Weight: 564
S)-AHPC hydrochloride Synonyms VH 032 CAS Number 1448189-80-7 Related CAS 1448297-52-6 (free base) Molecular Formula C22H32Cl2N4O3S Molecular Weight 503
Development of BODIPY FL VH032 as a High-Affinity and Selective von Hippel-Lindau E3 Ligase Fluorescent Probe and Its Application in a Time-Resolved Fluorescence Resonance Energy-Transfer Assay
88 SMILES: NCCCCC(NS(=O)(=O)C1=CC=C(C(=C1)C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S([O-])(=O)=O)C(O)=O
Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Size:25mg Cy3 CAS Number: N/A MolecularSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
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