Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) dbco-propionyl Product Name DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Synonyms CAS

Product Name DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C71H86N10O22 Molecular Weight 1431

this product contains a PEG4 linker instead of PEG2

495 SMILES: NCCCCC(NC(=O)C1=CC=C2C(=C1)C(=O)OC21C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2)C(O)=O Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

CC-92480 promotes rapid and extensive degradation of Aiolos/Ikaros than s lenalidomide and pomalidomide

Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) dbco-propionyl Product Name DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker