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Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg Product Name BGSN3 Synonyms N-(4-(((2-amino-9H-purin-6-yl)oxy)methyl)benzyl)-4-azidobutanamide

SKU 21529790240
4.6
USD445.00 USD476.00

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Description

Product Name BGSN3 Synonyms N-(4-(((2-amino-9H-purin-6-yl)oxy)methyl)benzyl)-4-azidobutanamide CAS Number Related CAS Molecular Formula C17H19N9O2 Molecular Weight 381

Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C89H151N13O26 Molecular Weight 1819

722 SMILES: [O-]C(=O)C1=CC=C(C=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCCCN=[N]#N Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

591 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8)-MMAE Size:10mg Product Name BGSN3 Synonyms N-(4-(((2-amino-9H-purin-6-yl)oxy)methyl)benzyl)-4-azidobutanamideSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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