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CA-DOTA-tris(t-Bu) can be used to attach DOTA moiety to protein
highlighting its strong affinity and potential as a precision tool in targeted protein degradation studies
253 Purity (HPLC) >= 95% Solubility DMSO
Product Name DOTA-tris(t-Bu)ester-PEG2-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C34H64N8O9 Molecular Weight 728
Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan AHPC CA-DOTA-tris(t-Bu) can be used toSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent
