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where multiple targets can be visualized simultaneously
Product Name DOTA-PEG2-C2-propanamido-maleimide Synonyms CAS Number Related CAS Molecular Formula C29H47N7O12 Molecular Weight 685
Product Name Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C67H86FN9O21 Molecular Weight 1372
324 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan payload where multiple targets can beSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
