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Product Name Thalidomide-O-acetamido-PEG3-C2-acid Synonyms Thalidomide-4'-O-acetamido-PEG3-C2-acid CAS Number n/a Related CAS Molecular Formula C24H29N3O11 Molecular Weight 535
CA-N3 is a HaloTag ligand containing an azide functional group
such as sodium 2-mercaptoethanesulfonate (MESNA)
Identification of Potent
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-Exatecan Size:10mg Product Name Thalidomide-O-acetamido-PEG3-C2-acid Synonyms Thalidomide-4'-O-acetamido-PEG3-C2-acidSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
