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Product Name MaP555-DBCO Synonyms CAS Number n/a Related CAS Molecular Formula C45H42N6O6S Molecular Weight 794
Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C87H140N14O26 Molecular Weight 1798
493 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)ON2C(=O)CCC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Cy3 maleimide
Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-Exatecan carboxylic acid Product Name MaP555-DBCO Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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