Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg The biotinylated biomolecules can then

The biotinylated biomolecules can then be bound to avidin or streptavidin

Carboxylic acids of proteins and other water-soluble biopolymers can be coupled to this molecule in aqueous solution using water-soluble carbodiimides such as EDAC

Product Name 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethan-1-amine Synonyms 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethanamine CAS Number 135630-61-4 Related CAS Molecular Formula C12H27N5 Molecular Weight 241

662 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg The biotinylated biomolecules can thenSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly