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Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg 251 Purity (HPLC) >= 95%

SKU 15318375941
4.1
EUR445.00 EUR475.00

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Description

251 Purity (HPLC) >= 95% Solubility DMSO

Product Name Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C76H106FN9O24 Molecular Weight 1548

Datasheet        MSDS

S)-AHPC-acetamido-O-PEG1-C2-Cl Synonyms CAS Number n/a Related CAS Molecular Formula C28H39ClN4O6S Molecular Weight 595

Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg 251 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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