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NRX-252114 is an enhancer of the interaction between beta-catenin and beta-TrCP
S)-AHPC-acetamido-O-PEG3-C2-azide Synonyms CAS Number 1797406-81-5 Related CAS Molecular Formula C32H47N7O8S Molecular Weight 689
Trametiglue acts as molecular glue
579 SMILES O=C1N(CC2=C(NCCOCCOCCOCCOCCOCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP chemical NRX-252114 is an enhancer ofSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
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